Reclast interactions with naproxen?

Hello,

There is a moderate interaction, moderate meaning:

Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.

Interactions between your drugs
Moderate
naproxen zoledronic acid
Applies to: Aleve (naproxen), Reclast (zoledronic acid)

Talk to your doctor before using zoledronic acid together with naproxen. If you take a medication like zoledronic acid by mouth, combining it with naproxen may increase your risk of developing gastrointestinal ulcers and bleeding. Contact your doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools. On the other hand, if you receive a medication like zoledronic acid by IV infusion, you may have an increased risk of kidney problems if you also use naproxen on a regular or long-term basis. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek medical attention if you experience signs and symptoms that may suggest kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Be sure to drink plenty of fluids if you develop diarrhea or vomiting during treatment with these medications, as dehydration can also affect the kidney. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Interaction report:
https://www.drugs.com/interactions-check.php?drug_list=1690-2475,2331-10724

Talk to your DR. about this potential moderate interaction.

Regards, masso