Rexulti Alternatives Compared
Rexulti | Wellbutrin XL | Zoloft |
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Rexulti (brexpiprazole) | Wellbutrin XL (bupropion) | Zoloft (sertraline) |
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Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression, Seasonal Affective Disorder. Wellbutrin XL may also be used for purposes not listed in this medication guide. |
Prescription only
Zoloft is a brand name for sertraline which is an effective antidepressant with less potential for drowsiness than many other antidepressants. It belongs to the group of medicines called selective... View more |
Related suggestions Depression
Major Depressive Disorder
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More about Rexulti (brexpiprazole) | More about Wellbutrin XL (bupropion) | More about Zoloft (sertraline) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Rexulti has an average rating of 6.5 out of 10 from a total of 458 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 27% reported a negative effect. |
Wellbutrin XL has an average rating of 7.5 out of 10 from a total of 482 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 15% reported a negative effect. |
Zoloft has an average rating of 7.2 out of 10 from a total of 1938 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 19% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Rexulti side effects in more detail. |
See also: Wellbutrin XL side effects in more detail. |
See also: Zoloft side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Rexulti prices |
View all Wellbutrin XL prices |
View all Zoloft prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
91 hours |
30 hours |
66 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 580 drugs are known to interact with Rexulti:
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A total of 497 drugs are known to interact with Wellbutrin XL:
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A total of 656 drugs are known to interact with Zoloft:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
July 10, 2015 |
August 28, 2003 |
December 30, 1991 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.